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Prevalence of co-morbidities and evaluation of their monitoring in Korean patients with rheumatoid arthritis: comparison with the results of an international, cross-sectional study (COMORA).

Identifieur interne : 000371 ( Main/Exploration ); précédent : 000370; suivant : 000372

Prevalence of co-morbidities and evaluation of their monitoring in Korean patients with rheumatoid arthritis: comparison with the results of an international, cross-sectional study (COMORA).

Auteurs : In Ah Choi [Corée du Sud] ; Sung Hwan Park [Corée du Sud] ; Hoon-Suk Cha [Corée du Sud] ; Won Park [Corée du Sud] ; Hyun Ah Kim [Corée du Sud] ; Dae-Hyun Yoo [Corée du Sud] ; Han Joo Baek [Corée du Sud] ; Seong Geun Lee [Corée du Sud] ; Yun Jong Lee [Corée du Sud] ; Yong Bum Park [Corée du Sud] ; Seung-Cheol Shim [Corée du Sud] ; Ihsane Hmamouchi [Maroc] ; Yeong Wook Song [Corée du Sud]

Source :

RBID : pubmed:28261976

Descripteurs français

English descriptors

Abstract

AIM

We designed this study to evaluate the prevalence of comorbidities, their monitoring states and association with treatment medication in Korean rheumatoid arthritis (RA) patients compared with patients from other countries.

METHODS

We analyzed 1050 RA patients from 11 Korean centers and compared them with 3520 patients from 16 other countries using an international, cross-sectional study evaluating comorbidities of RA (COMORA) database.

RESULTS

Annual evaluations of cardiovascular (CV) risk were less frequently performed in Korea (P = 0.0011). The prevalence of CV-associated morbidity was similar between Korean and international RA patients, although the proportions of current smokers, patients with a family history of CV disease, patients with hyperlipidemia, and patients with Framingham score > 20% were significantly lower in Korea (P < 0.0001 for all), and the antiplatelet agents were more optimally used in Korea (P = 0.0004). Prostate cancer screening was less frequently performed compared to other countries (P < 0.0001). Less than 10% of Korean RA patients were given influenza and pneumococcal vaccinations according to current recommendations.

CONCLUSIONS

There are differences in the prevalence of comorbidities and monitoring states of the risk factors between patients in Korea and in other countries. The prevalence of CV morbidity was similar between the two groups although the prevalence of CV risk factors was significantly low in Korea, suggesting that rheumatologists in Korea need to pay more attention to yearly CV risk monitoring, in addition to the screening of malignancy and vaccination of RA patients against infectious diseases.


DOI: 10.1111/1756-185X.13013
PubMed: 28261976


Affiliations:


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Le document en format XML

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<name sortKey="Kim, Hyun Ah" sort="Kim, Hyun Ah" uniqKey="Kim H" first="Hyun Ah" last="Kim">Hyun Ah Kim</name>
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<name sortKey="Yoo, Dae Hyun" sort="Yoo, Dae Hyun" uniqKey="Yoo D" first="Dae-Hyun" last="Yoo">Dae-Hyun Yoo</name>
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<name sortKey="Baek, Han Joo" sort="Baek, Han Joo" uniqKey="Baek H" first="Han Joo" last="Baek">Han Joo Baek</name>
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<name sortKey="Lee, Seong Geun" sort="Lee, Seong Geun" uniqKey="Lee S" first="Seong Geun" last="Lee">Seong Geun Lee</name>
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<name sortKey="Lee, Yun Jong" sort="Lee, Yun Jong" uniqKey="Lee Y" first="Yun Jong" last="Lee">Yun Jong Lee</name>
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<name sortKey="Song, Yeong Wook" sort="Song, Yeong Wook" uniqKey="Song Y" first="Yeong Wook" last="Song">Yeong Wook Song</name>
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<nlm:affiliation>Department of Molecular Medicine and Biopharmaceutical Sciences, Medical Research Center, Seoul National University, Seoul, Korea.</nlm:affiliation>
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<name sortKey="Choi, In Ah" sort="Choi, In Ah" uniqKey="Choi I" first="In Ah" last="Choi">In Ah Choi</name>
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<nlm:affiliation>Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.</nlm:affiliation>
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<settlement type="city">Séoul</settlement>
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<name sortKey="Cha, Hoon Suk" sort="Cha, Hoon Suk" uniqKey="Cha H" first="Hoon-Suk" last="Cha">Hoon-Suk Cha</name>
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<nlm:affiliation>Division of Rheumatology, Department of Internal Medicine, Samsung Medical Center, Seoul, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
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<name sortKey="Park, Won" sort="Park, Won" uniqKey="Park W" first="Won" last="Park">Won Park</name>
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<name sortKey="Kim, Hyun Ah" sort="Kim, Hyun Ah" uniqKey="Kim H" first="Hyun Ah" last="Kim">Hyun Ah Kim</name>
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<nlm:affiliation>Division of Rheumatology, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
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<name sortKey="Yoo, Dae Hyun" sort="Yoo, Dae Hyun" uniqKey="Yoo D" first="Dae-Hyun" last="Yoo">Dae-Hyun Yoo</name>
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<nlm:affiliation>Division of Rheumatology, Department of Internal Medicine, Hanyang University Medical Center, Seoul, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Division of Rheumatology, Department of Internal Medicine, Hanyang University Medical Center, Seoul</wicri:regionArea>
<placeName>
<settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Baek, Han Joo" sort="Baek, Han Joo" uniqKey="Baek H" first="Han Joo" last="Baek">Han Joo Baek</name>
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<nlm:affiliation>Division of Rheumatology, Department of Internal Medicine, Gachon Medical School Gil Medical Center, Incheon, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Division of Rheumatology, Department of Internal Medicine, Gachon Medical School Gil Medical Center, Incheon</wicri:regionArea>
<wicri:noRegion>Incheon</wicri:noRegion>
</affiliation>
</author>
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<name sortKey="Lee, Seong Geun" sort="Lee, Seong Geun" uniqKey="Lee S" first="Seong Geun" last="Lee">Seong Geun Lee</name>
<affiliation wicri:level="1">
<nlm:affiliation>Division of Rheumatology, Department of Internal Medicine, Pusan National University Hospital, Busan, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Division of Rheumatology, Department of Internal Medicine, Pusan National University Hospital, Busan</wicri:regionArea>
<wicri:noRegion>Busan</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Lee, Yun Jong" sort="Lee, Yun Jong" uniqKey="Lee Y" first="Yun Jong" last="Lee">Yun Jong Lee</name>
<affiliation wicri:level="1">
<nlm:affiliation>Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam</wicri:regionArea>
<wicri:noRegion>Seongnam</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Park, Yong Bum" sort="Park, Yong Bum" uniqKey="Park Y" first="Yong Bum" last="Park">Yong Bum Park</name>
<affiliation wicri:level="3">
<nlm:affiliation>Division of Rheumatology, Department of Internal Medicine, Yonsei University Severance Hospital, Seoul, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Division of Rheumatology, Department of Internal Medicine, Yonsei University Severance Hospital, Seoul</wicri:regionArea>
<placeName>
<settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Shim, Seung Cheol" sort="Shim, Seung Cheol" uniqKey="Shim S" first="Seung-Cheol" last="Shim">Seung-Cheol Shim</name>
<affiliation wicri:level="1">
<nlm:affiliation>Division of Rheumatology, Department of Internal Medicine, Eulji University Hospital, Daejeon, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Division of Rheumatology, Department of Internal Medicine, Eulji University Hospital, Daejeon</wicri:regionArea>
<wicri:noRegion>Daejeon</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Hmamouchi, Ihsane" sort="Hmamouchi, Ihsane" uniqKey="Hmamouchi I" first="Ihsane" last="Hmamouchi">Ihsane Hmamouchi</name>
<affiliation wicri:level="3">
<nlm:affiliation>Rheumatology Department, Faculty of Medicine, Laboratory of Clinical Research and Epidemiology, El Ayachi Hospital, Mohammed V University, Rabat, Morocco.</nlm:affiliation>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea>Rheumatology Department, Faculty of Medicine, Laboratory of Clinical Research and Epidemiology, El Ayachi Hospital, Mohammed V University, Rabat</wicri:regionArea>
<placeName>
<settlement type="city">Rabat</settlement>
<region nuts="2">Rabat-Salé-Kénitra</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Song, Yeong Wook" sort="Song, Yeong Wook" uniqKey="Song Y" first="Yeong Wook" last="Song">Yeong Wook Song</name>
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<nlm:affiliation>Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul</wicri:regionArea>
<placeName>
<settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<nlm:affiliation>Department of Molecular Medicine and Biopharmaceutical Sciences, Medical Research Center, Seoul National University, Seoul, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Molecular Medicine and Biopharmaceutical Sciences, Medical Research Center, Seoul National University, Seoul</wicri:regionArea>
<placeName>
<settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
<orgName type="university">Université nationale de Séoul</orgName>
</affiliation>
</author>
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<series>
<title level="j">International journal of rheumatic diseases</title>
<idno type="eISSN">1756-185X</idno>
<imprint>
<date when="2018" type="published">2018</date>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Arthritis, Rheumatoid (diagnosis)</term>
<term>Arthritis, Rheumatoid (epidemiology)</term>
<term>Cardiovascular Diseases (diagnosis)</term>
<term>Cardiovascular Diseases (epidemiology)</term>
<term>Cardiovascular Diseases (prevention & control)</term>
<term>Comorbidity (MeSH)</term>
<term>Cross-Sectional Studies (MeSH)</term>
<term>Databases, Factual (MeSH)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Immunization (MeSH)</term>
<term>Influenza Vaccines (administration & dosage)</term>
<term>Influenza, Human (diagnosis)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (prevention & control)</term>
<term>Male (MeSH)</term>
<term>Mass Screening (methods)</term>
<term>Middle Aged (MeSH)</term>
<term>Neoplasms (diagnosis)</term>
<term>Neoplasms (epidemiology)</term>
<term>Pneumococcal Infections (diagnosis)</term>
<term>Pneumococcal Infections (epidemiology)</term>
<term>Pneumococcal Infections (prevention & control)</term>
<term>Pneumococcal Vaccines (administration & dosage)</term>
<term>Prevalence (MeSH)</term>
<term>Protective Factors (MeSH)</term>
<term>Republic of Korea (epidemiology)</term>
<term>Risk Factors (MeSH)</term>
<term>Time Factors (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Bases de données factuelles (MeSH)</term>
<term>Comorbidité (MeSH)</term>
<term>Dépistage de masse (méthodes)</term>
<term>Facteurs de protection (MeSH)</term>
<term>Facteurs de risque (MeSH)</term>
<term>Facteurs temps (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Grippe humaine (diagnostic)</term>
<term>Grippe humaine (prévention et contrôle)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Humains (MeSH)</term>
<term>Immunisation (MeSH)</term>
<term>Infections à pneumocoques (diagnostic)</term>
<term>Infections à pneumocoques (prévention et contrôle)</term>
<term>Infections à pneumocoques (épidémiologie)</term>
<term>Maladies cardiovasculaires (diagnostic)</term>
<term>Maladies cardiovasculaires (prévention et contrôle)</term>
<term>Maladies cardiovasculaires (épidémiologie)</term>
<term>Mâle (MeSH)</term>
<term>Polyarthrite rhumatoïde (diagnostic)</term>
<term>Polyarthrite rhumatoïde (épidémiologie)</term>
<term>Prévalence (MeSH)</term>
<term>République de Corée (épidémiologie)</term>
<term>Sujet âgé (MeSH)</term>
<term>Tumeurs (diagnostic)</term>
<term>Tumeurs (épidémiologie)</term>
<term>Vaccins antigrippaux (administration et posologie)</term>
<term>Vaccins antipneumococciques (administration et posologie)</term>
<term>Études transversales (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en">
<term>Influenza Vaccines</term>
<term>Pneumococcal Vaccines</term>
</keywords>
<keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr">
<term>Vaccins antigrippaux</term>
<term>Vaccins antipneumococciques</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Arthritis, Rheumatoid</term>
<term>Cardiovascular Diseases</term>
<term>Influenza, Human</term>
<term>Neoplasms</term>
<term>Pneumococcal Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr">
<term>Grippe humaine</term>
<term>Infections à pneumocoques</term>
<term>Maladies cardiovasculaires</term>
<term>Polyarthrite rhumatoïde</term>
<term>Tumeurs</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>Arthritis, Rheumatoid</term>
<term>Cardiovascular Diseases</term>
<term>Influenza, Human</term>
<term>Neoplasms</term>
<term>Pneumococcal Infections</term>
<term>Republic of Korea</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Mass Screening</term>
</keywords>
<keywords scheme="MESH" qualifier="méthodes" xml:lang="fr">
<term>Dépistage de masse</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en">
<term>Cardiovascular Diseases</term>
<term>Influenza, Human</term>
<term>Pneumococcal Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr">
<term>Grippe humaine</term>
<term>Infections à pneumocoques</term>
<term>Maladies cardiovasculaires</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr">
<term>Grippe humaine</term>
<term>Infections à pneumocoques</term>
<term>Maladies cardiovasculaires</term>
<term>Polyarthrite rhumatoïde</term>
<term>République de Corée</term>
<term>Tumeurs</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Comorbidity</term>
<term>Cross-Sectional Studies</term>
<term>Databases, Factual</term>
<term>Female</term>
<term>Humans</term>
<term>Immunization</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prevalence</term>
<term>Protective Factors</term>
<term>Risk Factors</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Bases de données factuelles</term>
<term>Comorbidité</term>
<term>Facteurs de protection</term>
<term>Facteurs de risque</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Immunisation</term>
<term>Mâle</term>
<term>Prévalence</term>
<term>Sujet âgé</term>
<term>Études transversales</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>
<b>AIM</b>
</p>
<p>We designed this study to evaluate the prevalence of comorbidities, their monitoring states and association with treatment medication in Korean rheumatoid arthritis (RA) patients compared with patients from other countries.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>METHODS</b>
</p>
<p>We analyzed 1050 RA patients from 11 Korean centers and compared them with 3520 patients from 16 other countries using an international, cross-sectional study evaluating comorbidities of RA (COMORA) database.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
</p>
<p>Annual evaluations of cardiovascular (CV) risk were less frequently performed in Korea (P = 0.0011). The prevalence of CV-associated morbidity was similar between Korean and international RA patients, although the proportions of current smokers, patients with a family history of CV disease, patients with hyperlipidemia, and patients with Framingham score > 20% were significantly lower in Korea (P < 0.0001 for all), and the antiplatelet agents were more optimally used in Korea (P = 0.0004). Prostate cancer screening was less frequently performed compared to other countries (P < 0.0001). Less than 10% of Korean RA patients were given influenza and pneumococcal vaccinations according to current recommendations.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>CONCLUSIONS</b>
</p>
<p>There are differences in the prevalence of comorbidities and monitoring states of the risk factors between patients in Korea and in other countries. The prevalence of CV morbidity was similar between the two groups although the prevalence of CV risk factors was significantly low in Korea, suggesting that rheumatologists in Korea need to pay more attention to yearly CV risk monitoring, in addition to the screening of malignancy and vaccination of RA patients against infectious diseases.</p>
</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>Corée du Sud</li>
<li>Maroc</li>
</country>
<region>
<li>Rabat-Salé-Kénitra</li>
<li>Région capitale de Séoul</li>
</region>
<settlement>
<li>Rabat</li>
<li>Séoul</li>
</settlement>
<orgName>
<li>Université nationale de Séoul</li>
</orgName>
</list>
<tree>
<country name="Corée du Sud">
<region name="Région capitale de Séoul">
<name sortKey="Choi, In Ah" sort="Choi, In Ah" uniqKey="Choi I" first="In Ah" last="Choi">In Ah Choi</name>
</region>
<name sortKey="Baek, Han Joo" sort="Baek, Han Joo" uniqKey="Baek H" first="Han Joo" last="Baek">Han Joo Baek</name>
<name sortKey="Cha, Hoon Suk" sort="Cha, Hoon Suk" uniqKey="Cha H" first="Hoon-Suk" last="Cha">Hoon-Suk Cha</name>
<name sortKey="Kim, Hyun Ah" sort="Kim, Hyun Ah" uniqKey="Kim H" first="Hyun Ah" last="Kim">Hyun Ah Kim</name>
<name sortKey="Lee, Seong Geun" sort="Lee, Seong Geun" uniqKey="Lee S" first="Seong Geun" last="Lee">Seong Geun Lee</name>
<name sortKey="Lee, Yun Jong" sort="Lee, Yun Jong" uniqKey="Lee Y" first="Yun Jong" last="Lee">Yun Jong Lee</name>
<name sortKey="Park, Sung Hwan" sort="Park, Sung Hwan" uniqKey="Park S" first="Sung Hwan" last="Park">Sung Hwan Park</name>
<name sortKey="Park, Won" sort="Park, Won" uniqKey="Park W" first="Won" last="Park">Won Park</name>
<name sortKey="Park, Yong Bum" sort="Park, Yong Bum" uniqKey="Park Y" first="Yong Bum" last="Park">Yong Bum Park</name>
<name sortKey="Shim, Seung Cheol" sort="Shim, Seung Cheol" uniqKey="Shim S" first="Seung-Cheol" last="Shim">Seung-Cheol Shim</name>
<name sortKey="Song, Yeong Wook" sort="Song, Yeong Wook" uniqKey="Song Y" first="Yeong Wook" last="Song">Yeong Wook Song</name>
<name sortKey="Song, Yeong Wook" sort="Song, Yeong Wook" uniqKey="Song Y" first="Yeong Wook" last="Song">Yeong Wook Song</name>
<name sortKey="Yoo, Dae Hyun" sort="Yoo, Dae Hyun" uniqKey="Yoo D" first="Dae-Hyun" last="Yoo">Dae-Hyun Yoo</name>
</country>
<country name="Maroc">
<region name="Rabat-Salé-Kénitra">
<name sortKey="Hmamouchi, Ihsane" sort="Hmamouchi, Ihsane" uniqKey="Hmamouchi I" first="Ihsane" last="Hmamouchi">Ihsane Hmamouchi</name>
</region>
</country>
</tree>
</affiliations>
</record>

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